Martyn Meade will relocate to the historic Manton stables after securing the purchase of much of the estate on Thursday.
Meade, who sent out his first Group One winner when Aclaim landed the Prix de la Foret on Arc day, has been training at Sefton Lodge in Newmarket but will now move his operation to Wiltshire.
He told the Guardian: "It's a fantastic opportunity to buy a place that's steeped in history. I've bought the major part of Manton, including all the gallops."
He added: "I'm going to develop what's called the Fyfield yard there, which has 80 boxes just now. I'll put another yard in and I'll be combining training with farming, which I've done before. We were a bit stuck at Sefton. You've only room for about 60 horses and you need more than that these days."
Manton was previously owned by Robert Sangster and trainers such as John Gosden, Barry Hills and Michael Dickinson are among others to have been based there, while Brian Meehan currently leases a stable.